Research Materials

The Full Investigation

Comprehensive documentation of our research into consciousness, including theoretical synthesis, simulation code, and experimental analysis.

Core Documents

Key Findings

Finding Status Source
OR timescales match neural processing (τ ~ 0.1s for 10^10 tubulins) Confirmed Calculation
10% hub bias → 60% global shift at criticality p < 0.0001 THRML simulation
Bidirectional control (Q+ promotes, Q- vetoes) p < 0.0001 Unified test (40 runs)
Xenon isotope spin effect (~20% potency difference) Experimental Li et al. 2018
Microtubule-stabilizer delays unconsciousness Experimental Bhatt et al. 2024
Tryptophan superradiance at body temperature Experimental Babcock et al. 2024

Key References

• Li et al. "Xenon and isoflurane produce different effects on rat neuronal nicotinic acetylcholine receptor..." Anesthesiology (2018)

• Bhatt et al. "Microtubule-stabilizing agent delays anesthetic-induced unconsciousness" eNeuro (2024)

• Babcock et al. "Ultraviolet superradiance from tryptophan..." J. Phys. Chem. B (2024) PMID 38641327

• Beggs & Plenz. "Neuronal avalanches in neocortical circuits" J. Neuroscience (2003)

• Hameroff & Penrose. "Consciousness in the universe: A review of the Orch-OR theory" Physics of Life Reviews (2014)

• Suzuki & Larkum. "General anesthesia decouples cortical pyramidal neurons" Cell (2020)

• Tegmark. "Importance of quantum decoherence in brain processes" Phys. Rev. E (2000) — critiqued in our synthesis

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